Open Label Pharmacokinetic Study of SAR302503 in Subjects With Renal Impairment

Inclusion criteria : * Male or female subjects, between 18 and 75 years of age, inclusive. * For subjects between ages 75 to 79 with the approval from sponsor's medical monitor. * Body weight between 50.0 and 115.0 kg, inclusive if male, and between 40.0 and 100.0 kg, inclusive if female, body mass index between 18.0 and 34.9 kg/m2, inclusive. * Stable chronic renal impairment, as defined by Cockcroft-Gault formula; * Laboratory parameters within the acceptable range for subjects with renal impairment. * Using a double contraception method. Exclusion criteria: * Uncontrolled clinically relevant cardiovascular, pulmonary, gastrointestinal, metabolic,hematological, neurological, psychiatric, systemic, ocular, gynecologic (if female), or infectious disease, or signs of acute illness * Active hepatitis, hepatic insufficiency * Acute renal failure (de novo or superimposed to preexisting chronic renal impairment), nephrotic syndrome * History of or current hematuria of urologic origin that limits the subject's participation in the study * Subjects requiring dialysis during the study. * Any significant change in chronic treatment medication within 14 days before inclusion. * Concomitant treatment with or use of drugs or herbal agents known to be at least moderate inhibitors or inducers CYP3A4, sensitive or narrow therapeutic index substrate of CYP3A4. * Concomitant treatment with gastric pH modifying agents (proton pump inhibitors and H2-blockers) is not allowed 7 days prior to a…