Free DNA and Nucleosome Concentrations in Pathological Pregnancies

Inclusion Criteria for all patients: * The patient must have given her informed and signed consent * The patient must be insured or beneficiary of a health insurance plan Inclusion Criteria for patients in group P: * The patient is pregnant and has complications typical of placental vascular disease (preeclampsia, eclampsia, HELLP syndrome, retro-placental hematoma, in utero fetal death) or venous thromboembolism (deep vein thrombosis, pulmonary embolism) Inclusion Criteria for patients in group T1: * The patient is available for 3 months of follow-up * The patient is a non-pregnant healthy volunteer * No identifiable chronic pathologies * No history of neoplastic disease * No history of chronic infectious disease * No acute disease (such as benign infection), now or within the past two weeks Inclusion Criteria for patients in group T2: * The patient is available for 7 months of follow-up * The patient is pregnant, with no identifiable pregnancy complications * No identifiable chronic pathologies * No history of neoplastic disease * No history of chronic infectious disease * No acute disease (such as benign infection), now or within the past two weeks Exclusion Criteria for all patients: * The patient is participating in another study (with the exception of the following studies: PAPILLO-PMA (2013-A00538-37), ElastoMAP (2013-A01148-37), ElastoDéclenche (2014-A00828-39), LXRs (2009-A00968-49), Bakri (2013-A00914-41), OASIS 2 (2013-A00022-43)). * The patient is in an e…