This multicenter, open-label, single-arm extension study will evaluate the long-term safety of tocilizumab (RoActemra/Actemra) in participants with RA. Participants who have completed the MA21488 (NCT00810199) core study and the ML21530 (NCT00754572) study and who could benefit from the study drug, according to the opinion of the investigator, will receive 8 milligrams per kilogram (mg/kg) of intravenous (IV) tocilizumab every 4 weeks. The anticipated time on study treatment is 104 weeks.
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Number of Participants With Serious Adverse Events (SAEs) and Non-Serious Adverse Events (NSAEs)
Timeframe: From Baseline up to approximately 2 years
Number of Participants With AEs Leading to Dose Modification or Study Discontinuation
Timeframe: From Baseline up to approximately 2 years
Number of Participants With AEs of Special Interest
Timeframe: From Baseline up to approximately 2 years