Collagen Injections for the Treatment of Acne Scars and Wrinkles (NCT01704209) | Clinical Trial Compass
TerminatedPhase 1
Collagen Injections for the Treatment of Acne Scars and Wrinkles
Stopped: Company stopped making product for cosmetic use. All consented subjects withdrew before any study interventions were performed.
United States4 participantsStarted 2013-04
Plain-language summary
The purpose of this study is to find out if autologous (your own) fibroblast injections are effective for the treatment of acne scars and wrinkles.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18 or over
* Bilateral acne scars or have moderate to severe wrinkles
* Subjects in good health
* Subjects has the willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator
Exclusion Criteria:
* Under 18 years of age
* Pregnancy or lactation
* recent Accutane use in the past 6 months
* prone to hypertrophic and keloidal scarring
* have excessively redundant skin in the treatment area or wrinkles longer than 20 cm total
* have a history of autoimmune disorders, organ transplantation, cancer not in remission, active or chronic skin disease
* have a history of basal-cell carcinoma
* have previously received autologous fibroblast treatment
* have undergone any confounding therapy in the lower two-thirds of the face within 1 year or any investigational treatment within 30 days.
* have an allergy to collagen, bovine products, local anesthetics, gentamicin, or amphotericin B
* subjects who are unable to understand the protocol or to give informed consent
* subjects with mental illness
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change from baseline of rater's comparisons at 6 months