VSL#3 and Spontaneous Bacterial Peritonitis

Inclusion criteria: * Participant is willing and able to give informed consent for participation in the study. * Male or Female, aged 18 years or above. * Diagnosed with required disease/severity/symptoms as outlined in 6.3.1. * Stable dose of current regular medication (e.g. diuretics, beta-blockers, vitamin supplementation) for at least 4 weeks prior to study entry. * Female participants of child bearing potential and male participants whose partner is of child bearing potential must be willing to ensure that they or their partner use effective contraception during the study and for 3 months thereafter * Participants have clinically acceptable laboratory tests and ECG within 14 days of enrolment. * Able (in the Investigators opinion) and willing to comply with all study requirements. Willing to allow their General Practitioner and consultant Exclusion criteria: * Female participants who is pregnant, lactating or planning pregnancy during the course of the study. * Presence of hepatocellular carcinoma * Scheduled elective surgery or other procedures requiring general anaesthesia during the study. * Participant who is terminally ill * Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study. * Use of antibiotics or probiotics in the last 2 weeks * Known hypersensitivity…