Dynamic Locking Screws 5.0 vs. Standard Locking Screws in Fracture of Distal Femur Treated With Locked Plate Fixation

Inclusion Criteria: * 21 years and older * Closed or open distal femur fracture (AO 33 A1-3, 33 C1-3) including distal femur fractures above a total knee arthroplasty * Ability to walk independently prior to injury * Eligible for treatment with ORIF of the distal femur with a large fragment locking plate (LISS, LCP) * Willing and able to comply with post-operative protocol and return for follow-up. * Ability to understand the content of the patient information / informed consent form and participate in the clinical investigation * Signed informed consent Exclusion Criteria: * Additional ipsi- or contralateral lower extremity fracture * Any kind of implant at the ipsilateral proximal femur * Pre-existing malunion or nonunion of the ipsilateral lower extremity * Segmental bone defect requiring bone grafting * More than 4 weeks between injury and surgery * Pathologic fracture due to a disease other than osteoporosis (eg, tumor, metastasis) * Polytrauma * Active malignancy * Any not medically managed severe systemic disease * Recent history of substance abuse (ie, recreational drugs, alcohol) that would preclude reliable assessment * Pregnancy or women planning to conceive within the study period * Prisoner * Participation in any other medical device or medicinal product study within the previous month that could influence the results of the present study