Vapocoolant (Pain Ease Medium Stream) for Intravenous Lines in Emergency Department Patients

Inclusion Criteria: * Patients needing intravenous cannulation * Adults age 18 years equal or greater than. * Stable patient * Mentally competent patient able to understand the consent form Exclusion Criteria: * Patients with any allergies to the spray components ( e.g.1,1,3,3, pentafluoropropane or 1,1,1,2 tetrafluoroethane ) * Critically ill or unstable patient (e.g. sepsis or shock) * Infants and children of age , \<18 years. * Pregnant * Intravenous cannulation site located in area of compromised blood supply. (ex: patients with Peripheral Vascular Disease , Raynaud's disease, gangrene, Buerger's disease) * Intravenous cannulation site located in area of insensitive skin; such as , patients with a peripheral neuropathy including diabetic neuropathy. * Patient intolerant of cold or with hypersensitivity to the cold. * Patient unable or unwilling to give consent.