RATIONALE: Computed tomographic colonography (CTC) has proven to be accurate in detecting colorectal neoplasms and may be a primary test in colorectal cancer screening. PURPOSE: This clinical trial will compare participation rate, diagnostic yield and costs of computed tomographic colonography, faecal occult blood test (FOBT) and colonoscopy (CO) as a primary screening test in a population-based programme.
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Participation rate to faecal occult blood test (FOBT), computed tomographic colonography (CTC) and colonoscopy
Timeframe: 2 years
Detection rate for cancer or advanced adenomas of CTC versus three rounds of FOBT every second year
Timeframe: 6 years
Referral rate for colonoscopy induced by primary CTC versus three rounds of FOBT every second year
Timeframe: 6 years
Costs of the three different screening strategies proposed
Timeframe: 6 years