Safety and Exercise Study of Two Doses of BMN 110 for Morquio A Syndrome

Inclusion Criteria: * Is willing and able to provide written, signed informed consent (or patient's legally authorized representative) after the nature of the study has been explained and prior to performance of any research- related procedure. Also, patients who do not meet country and local age requirements for informed consent must be willing and able to provide written assent (if required) and written informed consent by a legally authorized representative after the nature of the study has been explained, and prior to performance of any research-related procedure. * Has documented clinical diagnosis of Morquio A Syndrome (MPS IVA) based on clinical signs and symptoms of MPS IVA and documented reduced fibroblast or leukocyte N-acetylgalactosamine-6-sulfatase (GALNS) enzyme activity or genetic testing confirming diagnosis of MPS IVA. * Is at least 7 years of age * Is able to walk ≥ 200 meters as assessed by the 6-minute Walk Test (6MWT) * If sexually active, is willing to use an acceptable method of contraception while participating in the study * If female of childbearing potential, must have a negative pregnancy test at the Screening Visit and be willing to have additional pregnancy tests during the study * Is willing and able to perform all study procedures, including cardiopulmonary exercise testing (CPET) Exclusion Criteria: * Inability to perform an exercise test due to limited mobility * Body weight greater than 95 kg at Screening * Severe, untreated sleep apnea a…