Role of Beta-blockers in the Prevention on the Arisen of a Severe Sepsis (TESS)

Inclusion Criteria: * Common characteristics of cases and controls: * Patients aged of more than 18 years old * Hospitalized patients, during the period of study, via the ICU of the participating hospital center, for a community infectious pathology: * lower respiratory infections (pneumonia) * intra-abdominal infections (cholangitis, diverticulitis, peritonitis) * urinary parenchymal infection (pyelonephritis complicated or without abscess, prostatitis, orchitis, epididymitis) * infections of skin and soft tissue infections (cellulitis, fasciitis) * meningitis, endocarditis, osteo-articular infections, salpingitis Definition of cases: * Patient included in the study and admitted to the emergency service either directly from ICU or after a hospitalization in a specialty for severe sepsis or septic shock on their infectious disease community. Definition of controls: * Patient included in the study with an infectious disease community, admitted to a specialty, and have not progressed to severe sepsis or septic shock before being released from the hospital. Non inclusion Criteria: * Opposition of the patient to the IT processing of its data within the framework of this observational study. * Exclusion criteria: Occurrence, during hospitalization, a severe sepsis or septic shock associated with a nosocomial superinfection.