Typical Daily Experiences, Ischemia and Repolarization in Coronary Artery Disease

KEY INCLUSION CRITERIA: LOW RISK CAD SUBJECTS, EJECTION FRACTION \>35% * Proficient in English * At least 21 years of age or older * Stable coronary artery disease * Willing to participant in 3 days of Holter monitor recordings and respond to surveys on a study provided smartphone KEY EXCLUSION CRITERIA: LOW RISK CAD SUBJECTS \- Presence of bundle branch block evident on ECG KEY INCLUSION CRITERIA: HIGH RISK CAD Subjects, Ejection Fraction \<35% * Proficient in English * 21 years of age or older * Have stable coronary artery disease with a documented previous myocardial infarction * Recent ECHO, MUGA or angiography (\< 5year old) reflecting a left-ventricular ejection fraction \<35% * Single or dual chamber ICD, with a back up rate of ventricular pacing at \< 45 bpm * Willing to wear a Holter monitor for 3 days and respond to surveys on a study provided smartphone KEY EXCLUSION CRITERIA: HIGH RISK CAD, Ejection Fraction \<35% * An implanted cardiac resynchronization pacemaker with ICD (CRT-D) * Heart rhythm artificially continuously paced * Presence of a bundle branch block evident on any ECG KEY INCLUSION CRITERIA: OLDER HEALTHY COMPARISON * Proficient in English * 51 years of age or older * No history and evidence of ischemic heart disease * Normal screening ECG without evidence for rhythm abnormalities, conduction abnormalities, hypertrophy, or other pathologies * Age matched within 5 years to CAD patients * Negative treadmill/bicycle exercise test * Willing to we…