Clinical Trial of Desmopressin on Nocturia in Obstructive Sleep Apnoea Patients

Inclusion Criteria: * Adult male or female patient (aged\</=65 years old) * Obstructive sleep apnoea diagnosed by sleep study * Stable treatment on obstructive sleep apnoea and / or LUTS * Nocturia on average more than once per night * Having the ability to communicate and comply with the requirements of the study Exclusion Criteria: * Presence of urethral strictures and neurogenic bladder dysfunction * Clinical evidence of bladder stones, bladder tumor or an active urinary tract infection * History of prostate cancer or prostate specific antigen (PSA) level \> 10ng/ml or suspicious of prostate cancer on digital rectal examination (DRE), unless a transrectal biopsy of prostate has been performed and the presence of prostate cancer has been excluded. * Patient on intermittent self-catheterisation * Recent start or change of treatment on obstructive sleep apnoea and / or nocturia * Uncontrolled medical problems: e.g. Diabetes Mellitus or Diabetes insipidus * Hyponatraemia * Pregnancy