The ChAMP (Chondral Lesions And Meniscus Procedures) Trial (NCT01527201) | Clinical Trial Compass
CompletedNot Applicable
The ChAMP (Chondral Lesions And Meniscus Procedures) Trial
United States190 participantsStarted 2012-01
Plain-language summary
The purpose of this randomized controlled trial is to determine the effectiveness of treating cartilage lesions found during knee arthroscopy.
Who can participate
Age range
30 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients scheduled to undergo a meniscectomy
* Patients with chondral lesions found during meniscectomy
* Patients without chondral lesions are not eligible for randomization to one of the study arms, but will still be included in the study and observed after surgery
Exclusion Criteria:
* Osteochondritis dissecans
* Large chondral flaps judged to be impending loose bodies
* Joint space loss of affected compartment greater than 50% compared to opposite side
* Visible osteophytes of the medial or lateral compartment
* Previous knee surgery on the affected side
* Previous major knee trauma
* History of inflammatory joint disease, gout, or chondrocalcinosis
* Presence of worker's compensation claim
* Patients undergoing meniscal repair
* Patients undergoing microfracture for contained grade IV chondral lesions
* Presence of significant ligamentous instability in the operative knee (i.e., complete acruciate ligament (ACL) or posterior cruciate ligament (PCL) tear, grade III medial or lateral side instability)
* Major neurologic deficit
* Serious medical illness with limited life expectancy or that poses high intraoperative risk
* Pregnancy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.