TerminatedNot Applicable

Study of Mitomycin-C Application in Laryngotracheal Stenosis

Stopped: Due to poor patient accrual, the study was closed prior to reaching the desired study size

United States15 participantsStarted 2012-08

Plain-language summary

This is a randomized, prospective, double-blind, placebo-controlled clinical trial of the use of mitomycin-C topical application as an adjunctive treatment in the endoscopic surgical treatment of patients with laryngotracheal stenosis. We hypothesize that the use of mitomycin-C improves patient outcome in the endoscopic surgical treatment of laryngotracheal stenosis.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with laryngotracheal stenosis, including subglottic stenosis or tracheal stenosis * Patients with disease amenable to treatment with endoscopic CO2 laser radial incisions and balloon dilation * Age greater than or equal to 18 years Exclusion Criteria: * Age less than 18 years * Pregnancy * Patients with glottic and supraglottic stenosis * Patients with disease not amenable to treatment with endoscopic CO2 laser radial incisions and balloon dilation * Patients with cartilaginous subglottic or tracheal stenosis

What they're measuring

Time to Repeat Surgery

Timeframe: 24 months

Trial details

NCT IDNCT01523275

SponsorUniversity of California, San Francisco

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-02

Results submitted2019-04-04

View on ClinicalTrials.gov More Laryngeal Stenosis trials