Hormonal Deficiency in the Quality of Life of Patients With Traumatic Brain Injury

Inclusion Criteria: * All subjects must be between the ages of 18-65 * Documented moderate to severe Traumatic Brain Injury (TBI) at less than 4 months post injury. * Glasgow Coma Scale (GCS) equal to or greater than 12 * Patients volunteer to participate in the study, with a written informed consent signed * BMI between 17 kg/m2 - 30kg/m2 * Affiliation to a national health insurance program Exclusion Criteria: * Glasgow Coma Scale (GCS) ≥13 * History of TBI ≥4 months * Anterior hypopituitarism documented * History of radiotherapy * Liver dysfunction: total bilirubin \<20µmol/l and/or factor V\<60%) * Renal dysfunction: creatinine clearance \< 30 ml/mn (Cockcroft \& Gault) * Anyone who is currently taking or who has taken corticotherapy in the last 4 weeks before TBI * Pregnancy * Contraindications to MRI: * Patients who have a heart pacemaker * Patients who have a metallic foreign body (metal sliver) in their eye, or who have an aneurysm clip in their brain * Patients with severe claustrophobia