Intestinal Tuberculosis Diagnostics and the Differentiation From Crohn's Disease

Inclusion criteria

• ✓. Endoscopic apparent intestinal tuberculosis: transverse ulcers, pseudopolyps, involvement of fewer than four intestinal segments, patulous ileo-coecal valve
• ✓. Histological evidence of tubercles/granulomas with caseation necrosis in intestinal biopsies
• ✓. DNA of M.tb detected by PCR of intestinal biopsies
• ✓. Positive immunohistochemistry in intestinal biopsies.
• ✓. Histological demonstration of acid fast bacilli in a lesion.
• ✓. Clinical: inflammatory, perforating (fistulising) disease, obstructive symptoms secondary to small bowel stenosis or stricture.
• ✓. Endoscopic: deep linear or serpingenous ulcerations, discrete ulcers in normal appearing mucosa, cobble-stoning or discontinuous or asymmetrical inflammation.
• ✓. Radiographic: segmental disease (skip lesions), small bowel or colonic strictures, stenosis or fistula.