Desensitization Protocol for Highly Sensitized Patients on the Waiting List for Kidney Transplant (NCT01502267) | Clinical Trial Compass
UnknownPhase 2
Desensitization Protocol for Highly Sensitized Patients on the Waiting List for Kidney Transplant
South Korea2 participantsStarted 2010-01
Plain-language summary
The purpose of this study is to determine whether high dose IVIG and B cell depleting agents can be used effectively in highly sensitized wait-listed patients.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ā„ 18
* patients who are on the waiting list more than 4 years
* PRA I or II \> 50%
Exclusion Criteria:
* Recent recipients of any live attenuated vaccine(s) within 4 weeks
* Subjects who have received IVIG or B cell depleting agents previously
* Subjects with positive result for viral hepatitis(B,C) or HIV infection
* Subjects with active infection
* Lactating or pregnant females
* Subjects who have history of malignancy in recent 5years
* Subjects who have experience of treatment for the psychiatric problem in recent 6months
* Subjects who have hematologic abnormality (Hb \< 7g/dL, Platelet \< 100,000/mm3, AST/ALT \> 80IU)