Acupuncture Point Stimulation for Treatment of Chemotherapy Nausea and Vomiting (NCT01492569) | Clinical Trial Compass
WithdrawnNot Applicable
Acupuncture Point Stimulation for Treatment of Chemotherapy Nausea and Vomiting
Stopped: low accrual
United States0Started 2012-05
Plain-language summary
This randomized pilot clinical trial studies giving acupuncture in reducing nausea and vomiting in patients undergoing chemotherapy. Pressing and stimulating nerves at an acupuncture point on the inside of the wrist may help control nausea and vomiting during chemotherapy.
Who can participate
Age range
8 Years – 21 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patient with a planned admission for at least 24 hours for highly emetogenic or moderately emetogenic chemotherapy at Lucile Packard Children's Hospital or Packard El Camino.
* Planned to undergo at least 2 more cycles of chemotherapy.
* Can include but not limited to: children with high risk ALL, AML, Ewing's Sarcoma, Osteosarcoma
* History of vomiting with prior cycles of chemotherapy (2 episodes of emesis at minimum) despite use of conventional antiemetic medications.
* Age 8-21.
* Parent must be able to understand and willing to sign written informed consent document.
Exclusion Criteria:
* Prior knowledge of acupuncture or experience with acupuncture or acupressure.
* There will be no restrictions regarding use of other Investigational Agents.
* Comorbid Diseases:
* Diagnosis of any cardiac condition (cardiomyopathy, arrhythmia, pacemaker placement).
* Any diagnosis requiring pediatric intensive care unit admission.
* Patients with brain tumor, brain metastasis (these patients often require radiation and surgery in addition to chemotherapy which may confound the results)
* Concomitant radiation therapy during current chemotherapy cycle.
* Developmental delay patients with allergy to tape or leads will be excluded from the study.
* Pregnant patients will be excluded from the study.
* Cancer survivors will not be excluded from the study as long as they are undergoing chemotherapy treatment for their current cancer therapy.
* HIV-positive …
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of episodes of vomiting
Timeframe: During the first 24 hours of chemotherapy
2
Severity of nausea as recorded on the visual analogue scale (VAS)
Timeframe: During the first 24 hours of chemotherapy