CompletedNot Applicable

Study of Postoperative 3D-CRT/IMRT in Hepatocellular Carcinoma

China76 participantsStarted 2008-01

Plain-language summary

Hepatectomy is difficult when the tumor is adjacent to the big vessels of the liver and some patients can not receive radical resection. Such patients have high risk of recurrence. Tumor resection and postoperative radiation is an option for such patients to achieve radical treatment and radiation may reduce local recurrence.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * written informed consent provided * 18\~75 years old * patients with histopathological proved hepatocellular carcinoma received hepatectomy and had at least one risk factor of recurrence * without any lymph node or distant metastasis (any T N0M0) * liver function: Child-Pugh A or B * Performance status: Karnofsky (KPS)≥70 or world health organization(WHO) score 0,1 * life expectation\>6 months * no dysfunction of major organs * no prior radiotherapy * negative for human immunodeficiency virus syndrome (HIV) * Considerable to computed tomography(CT) simulation and 3D-CRT or IMRT Exclusion Criteria: * malignant tumors of other sits * combining severe diseases, such as acute myocardial infarction(AMI), arrhythmias, infection * surgery performed in other hospitals without details * pregnant woman or woman need to breast feed or woman with positive chorionic gonadotrophin (HCG)

What they're measuring

overall survival

Timeframe: 3 year

Trial details

NCT IDNCT01456156

SponsorChinese Academy of Medical Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-01

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