Supplementation With L. Reuteri in H. Pylori Infected Adults (NCT01449500) | Clinical Trial Compass
UnknownNot Applicable
Supplementation With L. Reuteri in H. Pylori Infected Adults
Slovakia56 participantsStarted 2011-10
Plain-language summary
To determine whether simultaneous use of L. reuteri ProGastria and proton pump inhibitors can eradicate H. pylori in humans in the absence of antibiotics.
Who can participate
Age range18 Years – 70 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Subjects aged 18-70 years
* Infection with H. pylori defined by endoscopic examination with biopsy H. pylori staining
* Non-ulcer dyspepsia
* Absence of other pathology as shown by basic clinical laboratory tests (blood and urine) as well as abdominal ultrasound
* No earlier eradication therapy for H. pylori infection
* Written informed consent
* Stated availability throughout the entire study period
* Mental ability to understand and willingness to fulfil all the details of the protocol.
Exclusion Criteria:
* Duodenal or gastric ulcer
* MALT lymphoma
* Gastric resection (at any time)
* First level relatives of gastric cancer patients
* Absence of GI symptoms
* Use of NSAIDs, aspirin or other anti-inflammatory drugs within 1 week (for occasional use) or 3 weeks (for chronic use) of inclusion
* Use of oral antibiotics and/or PPIs and/or H2-antagonists during the 2 weeks prior to ingestion of the study product
* Pregnancy
* Participation in other clinical trials
What they're measuring
1
Increase in the number of subjects with treatment success after 28 days of treatment with omeprazole + L. reuteri compared to those given omeprazole + placebo.