DNA Analysis in Samples From Younger Patients With Germ Cell Tumors and Their Parents or Siblings

Inclusion Criteria: * The patient is enrolled on COG-ACCRN07 * The patient has a primary diagnosis of germ cell tumor (GCT) including germinoma (ICCC 9060-9065) teratoma (9080-9084), embryonal carcinoma (9070-9072), yolk sac tumor (9071),choriocarcinoma (9100, 9103, 9104), and mixed GCT (9085, 9101, 9102, 9105) in all sites including the brain and central nervous system and registered with Children's Oncology Group (COG) by a North American member institution * The patient must be diagnosed with a germ cell tumor between July 1, 2008 and December 31, 2015 * The patient must be \< 20 years of age at the time of diagnosis * The patient must have at least one biological parent alive and willing to participate * In the event that one case parent cannot contribute DNA, a case sibling, defined as the biological brother or sister of the study subject, may donate instead * All questionnaire respondents must understand English or Spanish * Concomitant treatment on a therapeutic trial is not required