A Study to Evaluate Whether Losartan Protects the Kidney in Hypertensive Diabetic Participants Wi… (NCT01390415) | Clinical Trial Compass
CompletedNot Applicable
A Study to Evaluate Whether Losartan Protects the Kidney in Hypertensive Diabetic Participants With Microalbuminuria (MK0954-365 AM1)
136 participantsStarted 2008-09
Plain-language summary
This study will evaluate whether losartan protects the kidney in hypertensive Type II diabetic participants with microalbuminuria.
Who can participate
Age range20 Years – 70 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diabetes mellitus
* Hypertension and has received losartan 50 mg or losartan 100 mg for at least 6 months
* Microalbuminuria (defined as microalbuminuria \> 30 mg/g and \< 300 mg/g by spot urine test)
* Serum creatinine ≤1.5 mg/dL for men and ≤1.4mg/dL for women
* Urinalysis with white blood cells (WBC) \<5 cells per high power field
* Results of hemoglobin A1c (HbA1c), fasting blood glucose, serum creatinine, urine albumin/urine creatinine ratio and urinary analysis tests at baseline and 6 months after initiating the losartan therapy are available
* Medical history and co-morbidities (if available) listed in medical records
* Prescription information of antihypertensive regimen of losartan 50 mg or 100 mg available
Exclusion criteria:
* Treated with angiotensin-converting enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARB) before initiated treatment with losartan 50 mg or losartan 100 mg
* Enrollment in another clinical trial
What they're measuring
1
Number of Participants With Macroalbuminuria After 6 Months of Treatment