UnknownPhase 1

Therapeutic Effect of Quercetin and the Current Treatment of Erosive and Atrophic Oral Lichen Planus

Iran30 participantsStarted 2010-04

Plain-language summary

Lichen planus (LP) is a common chronic inflammatory mucocutaneous disease with an immunologic etiology ,which has number of different clinical forms. Alternative natural or herbal origine drugs with antioxidant and anti-inflammatory properties have been used individually or in combination with systemic corticosteroids in order to decrease adverse drug reactions. This study was conducted to evaluate the effect of quercetin on treatment of erosive -atrophic lesions of oral lichen planus (OLP).

Who can participate

Age range12 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * confirmation of clinical diagnosis of Atrophic and erosive lichen planus by histological examination * two weeks wash out periods after the last treatment * having the experience of atrophic and erosive lesion greater than 1 cm having the experience of pain and burning greater than 3.5 in VAS Score Exclusion Criteria: * confirmation of dysplasia and malignancy in histologic examination * confirmation of lichenoid reaction in histologic examination * pregnancy and breast feeding * using fluorokinolon and cyclosporin which interact with quercetin

What they're measuring

the effects of this Drug on OLP measured with VAS scale for pain and evaluation of intensity of lesions.

Timeframe: 2 months

Trial details

NCT IDNCT01375101

SponsorMashhad University of Medical Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2011-09

Contact for this trial

maryam amirchaghmaghi, assistant professor

0098-0511889201 amirchakhmaghim@mums.ac.ir

View on ClinicalTrials.gov More Atrophic Oral Lichen Planus trials