Fexinidazole (1200mg) Bioavailability Under Different Food Intake Conditions

Inclusion Criteria: * Male healthy volunteers 18 to 45 years of age, * All subjects to be of sub-Saharan African origins with both parents of sub- Saharan African origins too, * Male subjects with a body mass index (BMI) calculated as weight in kg/(height in m2) from 18 to 28 kg/m2 at screening, * Able to communicate well with the Investigator and research staff and to comply with the requirements of the entire study, * Provision of written informed consent to participate as shown by a signature on the volunteer consent form, * Light smokers (less than 10 cigarettes per day) or subjects who are non-smokers. No smoking (or use of smoking substitute e.g. nicotine patch) is permitted from screening throughout the study, * Normal arterial blood pressure (BP) and pulse rate or, if abnormal, considered not clinically significant by the principal Investigator. These will be measured after resting for 5 min, * Registered with the French Social Security in agreement with the French law on biomedical experimentation. Exclusion Criteria: * Who on direct questioning and physical examination have evidence of any clinically significant acute or chronic disease, including known or suspected Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV) or Hepatitis C Virus (HCV) infection, * With any clinically significant abnormality following review of pre-study laboratory tests (aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT) and alkaline phosphatase (ALP) must be with…