Pharmacodynamic Comparison of Truncal Blocks in Patients With or Without Metabolic Disease (Kidney Failure, Diabetes)

General Inclusion Criteria: * The patient must have given his/her informed and signed consent * The patient must be insured or beneficiary of a health insurance plan * The patient is available for 1 month of follow up * The patient is scheduled for hand or wrist surgery Inclusion Criteria for the "Renal Insufficiency" group * Patient has renal insufficiency as defined by a creatine clearance of \< 30ml/min without dialysis Inclusion Criteria for the "Diabetes" group * Patient has chronic hyperglycemia, either a fasting glycemia \> 1.26 g/l (7mmol/l) for longer than 5 years and receiving an oral, well-adjusted (last HBA1c \< 6.5%)), non-insulin, antidiabetic treatment Inclusion Criteria for the "Non-exposed" group * Patient without metabolic or neurologic disease, with creating clearance \> 90ml/min Exclusion Criteria: * The patient is participating in another study * The patient is in an exclusion period determined by a previous study * The patient is under judicial protection, under tutorship or curatorship * The patient refuses to sign the consent * It is impossible to correctly inform the patient * The patient is pregnant * The patient is breastfeeding * Patient weighs less than 50 kg * Score ASA \> 4 * contra indication for locoregional anesthesia * Severe metabolic and / or decompensated renal disease, cardiac or pulmonary decompensation * Associated peripheral neuropathy associated with diabetes or kidney disease * Associated central neuropathy associated (eg M…