Levonorgestrel-releasing Intrauterine Device on Obese Women: Effects on Hemostatic and Arterial Function

Inclusion Criteria: * Women 18 to 40 years of age with obesity grade I and II who wished to use a contraceptive Exclusion Criteria: * any clinical conditions corresponding to category 3 or 4 of the World Health Organization medical eligibility criteria for IUD-LNG or IUD-CU use smoking * alcoholism * illicit drug use * any systemic disease (systemic arterial hypertension, DM, immune system diseases or thyroid diseases) except PCOS * current or previous (up to two months before the study) use of oral, vaginal, monthly injectable or transdermal combined hormonal contraceptives current or previous use (up to six months before the study) of a long-lasting hormonal contraceptive method (injectable, implant or intrauterine device) * twelve weeks or less since childbirth * currently breastfeeding or had stopped breastfeeding within two months of the screening visit * chronic and/or acute inflammatory processes * use of drugs known to interfere with inflammatory markers or with CVD risk (anti-androgens, hypoglycemic drugs, anti-inflammatory drugs or statins)