Reverse Genetic H9N2 Influenza Vaccine Study in Adults

Inclusion Criteria: * Subject is 18 to 49 years of age, inclusive, on the day of screening * Subject has an understanding of the study and its procedures, agrees to its provisions, and gives written informed consent prior to study entry * Subject is generally healthy, as determined by the investigator's clinical judgement through collection of medical history and performance of a physical examination * Subject is physically and mentally capable of participating in the study as determined by the investigator * Subject agrees to keep a daily record of symptoms for the duration of the study * If female of childbearing potential, subject presents with a negative urine pregnancy test within 24 hours prior to first vaccination and agrees to employ adequate birth control measures for the duration of the study. For the purposes of this study at least one of the following types of US Food and Drug Administration (FDA) approved birth control measures shall be applied through completion of the Day 181 study visit: * Hormonal types of birth control (such as implants or birth control pills) or an intrauterine device * A barrier type of birth control measure (i.e. condoms, diaphragms, cervical caps, etc.) Exclusion Criteria: * Subject has a history of exposure to H9N2 influenza virus or a history of vaccination with an H9N2 influenza vaccine * Subject is at potential occupational risk of contracting H9N2 influenza infection (e.g. poultry workers) * Subject currently suffers from or…