CompletedPhase 4

Intravenous Paracetamol or Morphine for the Treatment of Acute Flank Pain

Turkey (Türkiye)73 participantsStarted 2011-01

Plain-language summary

STUDY OBJECTIVE: This randomized, controlled trial evaluates the analgesic efficacy and safety of intravenous single-dose paracetamol and morphine for the treatment of acute flank pain. METHODS: The investigators conducted a randomized, double-blind, controlled clinical trial comparing single intravenous doses of paracetamol (1 g) and morphine (0.1 mg/kg) for patients presenting to the emergency department (ED) with acute flank pain. Subjects with inadequate pain relief at 30 minutes received rescue fentanyl (0.75 microg/kg).

Who can participate

Age range16 Years – 55 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Adults (aged 16 to 55 years old) with acute low back pain were eligible for inclusion in the study Exclusion Criteria: * known allergy or contraindication to morphine, paracetamol, or any opioid analgesic * hemodynamic instability; fever (temperature \> 38°C \[100.4°F\]) * evidence of peritoneal inflammation * documented or suspected pregnancy * known or suspected aortic dissection or aneurysm * use of any analgesic within 6 hours of ED presentation * previous study enrollment Patients with known renal, pulmonary, cardiac, or hepatic failure, as well as those with renal transplantation, were also excluded.

What they're measuring

Reduction in visual analogue scale

Timeframe: 15 minutes interval

Trial details

NCT IDNCT01318187

SponsorPamukkale University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2011-03

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