A Phase III Clinical Trial to Evaluate the Protective Efficacy of Three Doses of Oral Rotavirus Vaccine (ORV) 116E

Inclusion Criteria: * At least one parent(s) or legally acceptable representative's consent for participation and are able to understand study procedures * Subjects aged 6 to 7 weeks at recruitment * No plans to move in the next 24 months Exclusion Criteria: * Administration of rotavirus vaccine in the past * Presence of any illness requiring hospital referral (temporary exclusion) * Known case of immunodeficiency disease, known HIV positive * Known case of chronic gastroenteritis disease * Any other conditions which in the judgment of the investigator warrant exclusion (e.g. no exclusion criteria but seems "ill", investigators suspects neglect) * Diarrhea on the day of enrollment (temporary exclusion)