RESPECT Trial - (Rapid Extravascular Sealing Via PercutanEous Collagen ImplanT)

Exclusion criteria

• ✕. Advanced refusal of blood transfusion, if necessary;
• ✕. Active systemic or a cutaneous infection or inflammation;
• ✕. Pre-existing immunodeficiency disorder and/or chronic use of systemic steroids;
• ✕. Known, significant history of bleeding diathesis, coagulopathy, von Willebrand's disease or current platelet count \< 100,000 cells/mm3, baseline INR ≥1.8, or fibrinogen level less than 150 mg/dl (if received a fibrinolytic agent within prior 24 hours);
• ✕. Severe co-existing morbidities having a life expectancy of less than 30 days;
• ✕. Currently involved in any other investigational clinical trial;
• ✕. Ipsilateral femoral arteriotomy within the previous 30 days;
• ✕. Planned endovascular procedure within the next 30 days;