A Study Evaluating the Safety of LEO 90105 and Its Vehicle, After Multiple Administration on Intact Skin of Healthy Japanese Male Subjects

Inclusion Criteria: * Healthy Japanese male subjects * Aged 20 to 40 years inclusive * Subjects without signs of skin irritation (erythema, dryness, roughness or scaling) on the test site * Subjects willing to follow the study procedures and complete the study * Subjects having understood and signed a written informed consent * Subjects without abnormal in physiological test and clinical test in screening, and also judged as possible to participant the study by investigators Exclusion Criteria: * Subjects with Body mass Index (BMI ) (body weight(kg)/height (m)²) outside the range 18-25 kg/m2(18≤BMI\<25) * Subjects with history of alcohol, chemical or drug abuse * Subjects with history of allergic reaction to any content of the study medication * Subjects with systemic or cutaneous disease that could in any way confound interpretation of the study results (e.g. atopic dermatitis, eczema, psoriasis) * Subjects with known sensitivity to any component of any of the formulations being tested * Subjects with known hepatic, renal or cardiac disorders * Subjects using systemic, locally injected or inhaled corticosteroids within 4 weeks of study start (Day 1) * Subjects using systemic vitamin D analogues,vitamin D or calcium supplements within 4 weeks of study start (Day 1) * Subjects using any drug (systemic or topical) within 2 weeks of study start (Day 1) * Subjects using non-marketed/other investigational products one month prior to or 5 half lives (for those the half life is l…