Biosynthesis of PGD2 in Vivo

Inclusion Criteria: age between 18-70 * subject must be in good health as based on medical history * All subjects must be non-smoking, non-pregnant volunteers * Female subjects of child bearing potential must be using a medically acceptable method of contraception throughout the entire study period. All female subjects must consent to a urine pregnancy test at screening and just prior to the start of each treatment period of the study, which must be negative at all time points. Exclusion Criteria: * subjects with any medical condition that according to the investigator may interfere with interpretation of the study results, be indicative of an underlying disease state, or compromise the safety of a potential subject. * subjects who have received an experimental drug within 30 days prior to the study. * subjects who have taken medications at least 10 days prior to the study. Birth Control pills are acceptable and shall not be excluded. * Subjects who have taken aspirin or aspirin containing products for at least 10 days prior to the study. * Subjects who have taken acetaminophen, NSAIDS, COX-2 inhibitors (OTC or prescription) for at least 10 days prior to the study. * Subjects who are currently consuming any type of tobacco product(s). * Subjects who consume high doses of antioxidant vitamins daily (vitamin C \> 1000mg, Vitamin E \> 400 IU, Beta Carotene \> 1000IU, Vitamin A \> 5000IU, Selenium \> 200mcg, Folic Acid \> 1mg) for the 2 weeks prior to the start of the study a…