Study to Compare TP-434 and Ertapenem in Community-acquired Complicated Intra-abdominal Infections

Inclusion Criteria: * Abdominal pain/discomfort with onset prior to hospitalization * Evidence of a systemic inflammatory response * Physical findings consistent with intra-abdominal infection (IAI) * Clinical diagnosis of community-acquired IAI requiring urgent surgical or percutaneous intervention and not expected to require antibacterial therapy for longer than 14 days * Body mass index (BMI) of ≤ 30 kilograms per square meter (kg/m\^2) * Able to provide informed consent. If the participant is unable to provide informed consent, the participant's legally acceptable representative may provide written consent in accordance with institutional guidelines * If female, not pregnant or nursing or, if of child-bearing potential either: will commit to use at least two medically accepted, effective methods of birth control (for example, condom, oral contraceptive, indwelling intrauterine device, hormonal implant/patch, injections, approved cervical ring) during study drug dosing and for 90 days following last study drug dose or practicing sexual abstinence Exclusion Criteria: * Symptoms related to diagnosis of complicated appendicitis (if current diagnosis) for \< 24 hours prior to current hospitalization * Previously hospitalized or admitted to a healthcare facility within the last 6 months * Managed by Staged Abdominal Repair or other open abdomen technique * Known at study entry to have an IAI caused by a pathogen(s) resistant to both study drug antibiotics * Acute Physiology …