Open-Labeled Study of PSI-7977 and RBV With and Without PEG-IFN in Treatment-Naïve Patients With HCV GT2 or GT3

Inclusion Criteria: * Chronic Genotype 2 or 3 HCV-infection or Genotype 1, serum HCV RNA ≥ 50,000 IU/mL * Not co-infected with HIV * Use of highly effective contraception methods if female of childbearing potential or sexually active male Exclusion Criteria: * History of any other clinically significant chronic liver disease * Pregnant or nursing female or male with pregnant female partner * History of significant drug allergy to nucleoside/nucleotide analogs. * Participation in a clinical study within 3 months prior to first dose * Positive result for significant drug use at Screening