Continuous Intraocular Pressure (IOP) Monitoring in Pigmentary Dispersion Syndrome and Pigmentary… (NCT01253109) | Clinical Trial Compass
TerminatedNot Applicable
Continuous Intraocular Pressure (IOP) Monitoring in Pigmentary Dispersion Syndrome and Pigmentary Glaucoma Patients
Stopped: Law agreement between Triggerfish signal and GAT IOP during both sessions. However, an increase in the Triggerfish signal was observed during jogging phase.
Switzerland15 participantsStarted 2010-09
Plain-language summary
This study monitors the intraocular pressure (IOP) over 4 to 6 hours using the SENSIMED Triggerfish® device and Goldmann Applanation Tonometry (GAT) in pigment dispersion syndrome and pigmentary glaucoma patients. The aim of the study is to detect SENSIMED Triggerfish® output signal peak after induced fluctuation by physical exercise or pupil dilation.
Who can participate
Age range18 Years – 60 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Confirmed diagnosis of pigmentary dispersion syndrome or pigmentary glaucoma on both eyes
* IOP of ≥ 15 mmHg
* 18-60 years.
* Patients able to jog continuously for at least 25 minutes
* Phakic eyes
* Patients who accept signing an informed consent approved by the Ethics Committee.
Exclusion Criteria:
* Pigmentary glaucoma already treated with peripheral laser iridotomy (PLI), argon laser peripheral iridoplasty (ALPI), argon laser trabeculoplasty (ALT) and selective laser trabeculoplasty (SLT) in any eye
* Patients treated with pilocarpine or other mydriatic agent within the last 4 weeks in any eye
* Anti-hypertensive treatment in the 4 weeks preceding the study and throughout the study. Following signature of informed consent, anti-hypertensive treatment will be washed out for 4 weeks prior to study procedures in enrolled patients
* Patients with pseudoexfoliative (PEX) syndrome or PEX glaucoma in any eye
* Patients not able to understand the nature of the research
* Patients under tutorship
* Corneal abnormality
* Subjects with contraindications for wearing contact lenses
* Full frame metal glasses during SENSIMED Triggerfish® monitoring
* History of other ocular surgery except uncomplicated strabismus surgery no later than 3 months prior to study procedures
* Ocular inflammation or infection
* History of cardiac or pulmonary disorder
* Pregnancy and lactation
* Simultaneous participation in other clinical research