Safety and Efficacy Study of Polydioxanone (PDS) Plates in Rhinoplasty

Inclusion Criteria: * Males and females between 18 and 65 years of age. * Subjects requesting primary or secondary rhinoplasty and requiring a CSE graft performed through an endonasal approach. * Subjects willing to undergo PDS plating. * Subjects with either ear conchal or septal cartilage available for grafting purposes. * Willingness and ability to comply with protocol requirements, including returning for follow-up visits and abstaining from exclusionary procedures for the duration of the study. * Willingness and ability to comply with the PI's standard preoperative and postoperative rhinoplasty instructions. * Subjects of childbearing potential must have a negative urine pregnancy test result at Visit 1 and be willing able to use an acceptable method of birth control (e.g., barrier methods used with a spermicidal agent, hormonal methods, IUD, surgical sterilization, abstinence) during the study. Women will not be considered of childbearing potential if one of the following is documented on the medical history: * postmenopausal for at least 12 months prior to study drug administration * without a uterus and/or both ovaries * has had a bilateral tubal ligation for at least 6 months prior to study drug administration. * absence of an other physical condition according to the PI's discretion * Willingness and ability to provide written photo consent and adherence to photography procedures (i.e., removal of jewelry and makeup). * Willingness and ability to provide written in…