Rifamycin SV-MMX® Tablets Versus Ciprofloxacin Capsules in Acute Traveller's Diarrhoea

Inclusion Criteria: * Signed informed consent, * Men or women between 18 and 85 years of age, * History of arriving from their country of residence in the industrialized part of the world within the past 4 weeks, * Presenting with acute infectious diarrhoea (defined as at least 3 unformed, watery or soft stools accompanied by symptoms within 24 hours preceding randomisation with duration of illness ≤ 72 hours), * Presence of one or more signs or symptoms of enteric infection (moderate to severe gas/flatulence, nausea, vomiting, abdominal cramps or pain, rectal tenesmus, fecal urgency), * Women of childbearing potential had to apply during the entire duration of the study a highly effective method of birth control Exclusion Criteria: * Residency in any country with high incidence rate of TD within the past 6 months, * Fever (defined as a body (oral) temperature \>100.4°F or 38.0°C; antipyretic medication should not have been administered in the 6 hours prior to this assessment), * Known or suspected infection with non-bacterial pathogen, * Presence of diarrhoea of \>72 hours duration, * Presence of grossly bloody stool, * Presence of moderate or severe dehydration (i.e. symptoms of hypovolemia such as orthostatic hypotension, dizziness or wrinkling of skin), * History of inflammatory bowel disease or celiac disease,