A Study of Medication With or Without Psychotherapy for Complicated Grief (NCT01179568) | Clinical Trial Compass
CompletedPhase 2
A Study of Medication With or Without Psychotherapy for Complicated Grief
United States395 participantsStarted 2010-03
Plain-language summary
The major goal of this 4-site, double blind, placebo-controlled intervention trial is to assess the efficacy of medication (Citalopram) alone or with psychotherapy (Complicated Grief Therapy) to treat the symptoms of complicated grief.
Who can participate
Age range18 Years – 95 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosed with Complicated Grief and this is the patient's most important (primary) problem
* Ability to give informed consent
* Fluent in English
* Willingness to have sessions audiotaped
* Willingness to undergo random assignment
Exclusion Criteria:
* Diagnosis of one or more of the following disorders: Schizophrenia or other psychotic disorder, current (past 6 months) substance abuse, Bipolar Disorder, current manic episode, Dementia
* Pregnant or lactating women and women of childbearing potential not using medically accepted forms of contraception
* Acute, unstable or severe medical illness such as (but not limited to) stroke, epilepsy, or other neurodegenerative disorders, metastatic or active cancer, hepatic disease, or primary renal disease requiring dialysis
* Prior intolerance of citalopram
* Pending or active disability claim or lawsuit related to the death
What they're measuring
1
Responder Status Based on Complicated Grief Clinical Global Impression-Improvement (CGI-I) Scale