Comparison of Breathing Event Detection by a Continuous Positive Airway Pressure Device to Clinical Polysomnography

Inclusion Criteria: * Males and females, ages 21-80. * Able and willing to provide written informed consent. * Diagnosis of complex sleep apnea (CompSAS) or Obstructive Sleep Apnea (OSA) within one year of study participation. * For participants with CompSAS: (a) Diagnostic PSG with an Apnea-Hyopnea Index (AHI) greater than or equal to 10 events/hour and central apnea index (CAI) greater than or equal to 5 events/hour of sleep or (b) PAP titration with a CAI greater than or equal to 5 events/hour of sleep. * For participants with OSA, a diagnostic PSG with an AHI greater than or equal to 15 events/hour of sleep. * Must have had a CPAP titration such that the necessary PAP level to treat the sleep disordered breathing is known. * Agreement to undergo a full-night, in-laboratory PSG on CPAP device. Exclusion Criteria: * Participation in an interventional research study within 30 days of study participation. * Pre-menopausal females known to be pregnant or who are sexually active and not using a reliable method of birth control. * Surgery of the upper airway, nose, sinus, or middle ear within the last 90 days. * Surgery at any time for the treatment of OSA such as uvulopalatopharyngoplasty (UPPP). * Major medical or psychiatric condition that would interfere with the demands of the study, adherence to positive airway pressure, or the ability to complete the study. * Chronic respiratory failure or insufficiency with suspected or known neuromuscular disease, moderate or severe …