By InvitationNot Applicable

Gene Expression in Inflammatory Bowel Disease

United States1,100 participantsStarted 1999-11

Plain-language summary

Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a idiopathic, chronic and frequently disabling inflammatory disorder of the intestines characterized by a dysregulated mucosal immune response that affect more than a million Americans. This protocol is aimed at obtaining tissue samples to test for expression of genes associated with IBD and to better understand the pathogenesis of IBD with the study of genetics, proteomics, physiologic processes and microbiomes (microbiology).

Who can participate

Age range7 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All persons, regardless of IBD affection status, greater than 7 years of age undergoing upper or lower endoscopy or bowel resection Exclusion Criteria: * Persons with bleeding tendencies * Persons on anti-coagulation therapy or who will be place on anti-coagulation therapy following the planned endoscopy procedures

What they're measuring

Gene Expression in IBD

Timeframe: Single visit, approximately 1 hour

Trial details

NCT IDNCT01171872

SponsorJohns Hopkins University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2032-12

View on ClinicalTrials.gov More Inflammatory Bowel Disease trials