Active — Not RecruitingNot Applicable

Johns Hopkins Crohn's Disease and Ulcerative Colitis Study

United States2,500 participantsStarted 1996-07

Plain-language summary

Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a idiopathic, chronic and frequently disabling inflammatory disorder of the intestines characterized by a dysregulated mucosal immune response that affect more than a million Americans. This current protocol was established in 1996 with the goal of identifying the genetic and environmental components that contribute to the development of IBD, especially in families.

Who can participate

Age range5 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: ADULTS: * Patients with IBD and family members who have or do not have IBD. * People that do not have IBD nor have a family member with IBD needed for comparison purposes. CHILDREN: * Children age 5 or older with IBD and family members who have or do not have IBD. * Children that do not have IBD nor have a family member with IBD needed for comparison purposes. Exclusion Criteria: * The only exclusions are age parameters and health reasons that would preclude enrollment; such as, for anemic patients. Blood-draws on anemic patients may, in certain medical cases, pose a health risk; therefore, the investigators request that if the participants are anemic that the participants present a letter from the participant's personal physician giving explicit permission for the participant to join if at the time it is clinically advisable.

What they're measuring

Genetics of IBD

Timeframe: Single visit, approximately 1 hour

Trial details

NCT IDNCT01169207

SponsorJohns Hopkins University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-12

View on ClinicalTrials.gov More Inflammatory Bowel Disease trials