Sunscreens in Patients With Cutaneous Lupus Erythematosus(CLE)

Inclusion Criteria: * Patients with subacute cutaneous lupus erythematosus (SCLE), discoid lupus erythematosus (DLE), or lupus erythematosus tumidus (LET) according to the Düsseldorf Classification 2004 (Kuhn and Ruzicka 2004) confirmed by histological analysis. * Women of childbearing potential with a negative pregnancy test at screening (urine test) and using a medically accepted contraceptive regimen (intra-uterine device, partner's vasectomy, \>3 months previous hormonal contraception (oestrogen plus gestagen pill, depot injections, or subcutaneous depot) combined with a barrier method (preservative, vaginal diaphragm, cervical cap, spermicide) during the study and for 8 weeks after the last UV exposure. * Women clinically sterile (post-menopausal, undergone hysterectomy or tubal ligation). * Actively cooperating to participate in the study, to follow the instructions of the investigator and to attend the centre at the agreed times. * Development of skin lesions any time under current systemic treatment if patient is receiving systemic medication for the treatment of CLE. * Signed informed consent form after the nature of the study has been fully explained. Exclusion Criteria: * Pregnancy or lactation and women with positive pregnancy test. * Known hypersensitivity or allergic contact reactions to components of the study agents. * Treatment with photosensitizing drugs. * Exposure to direct natural (sunlight) or artificial UV radiation on the back within 4 weeks prior t…