Exercise as a Treatment for Substance Use Disorders Protocol

Inclusion Criteria: * Male or female age 18-65. * Admitted to residential setting and receiving substance use treatment. * Ability to understand and willingness to provide written informed consent. * Agree to remain in facility for authorized treatment of about 21-30 days. * Willing to provide contact information. * Self-reported use of stimulant drug (cocaine, methamphetamine, amphetamine, or other stimulant, excluding caffeine and nicotine) within the 30 days prior to admission for treatment. * Meets DSM-IV criteria for substance abuse or dependence for stimulants (cocaine, methamphetamine, amphetamine, or other stimulant, excluding caffeine and nicotine) within the last 12 months. * Medical clearance with protocol-defined stress testing (in accordance with American College of Sports Medicine (ACSM) guidelines) from protocol approved medical personnel. Details of guidelines and related testing protocol are provided in the study Manual of Procedures. * Body mass index (BMI)≤40 kg/m2 or BMI 40 \>kg/m2 and cleared by medical personnel to exercise. * Able to comprehend and communicate in English. Exclusion Criteria: * Evidence of general medical condition or other abnormality that contraindicates use of exercise, based on the Medical Screening Visit. * Current opiate dependence. * Currently considered a high suicide risk and/or high risk for being unable to complete the study due to the need for psychiatric hospitalization, suicide attempts or suicidality, significant self-m…