Efficacy and Time and Resources for Hylenex-facilitated SC Rehydration Versus ORT for Dehydrated Children in the Emergency Department (ED)

Inclusion Criteria: * Male or female and aged 2 months to 2 years * Presenting to ED with mild or moderate dehydration * Candidate for both parenteral and oral rehydration therapies * Healthy, except for underlying etiology for dehydration * Naive to ORT or having received attempted ORT at home for current occurrence of dehydration. * Pre-dehydration body weight greater than 5th percentile for age Exclusion Criteria: * Severe dehydration * Shock or a life-threatening situation * Any condition precluding SC infusion or infusion site evaluation in all possible anatomical locations (upper back, anterior thighs, abdomen, other potential areas) for SC infusion * Medical reason or condition precluding administration of ORT * Indwelling IV catheter (except one intended only for laboratory sample collection) or anticipated need for IV therapy during the study * Anticipated need for hospitalization(other than for rehydration) * Known hypersensitivity to hyaluronidase or any other ingredient in the formulation of hylenex recombinant * Known hyponatremia, hypernatremia or hypokalemia * Medical condition likely to interfere with ability to fully complete protocol-specified interventions and assessments, or likely to prolong need for medical attention beyond that required for rehydration * Participation in an investigational drug or device study within 30 days before participation in this study