Effectiveness, Safety and Tolerability Study of RP-G28 for Symptoms Associated With Lactose Intolerance

Inclusion Criteria: * Male and female subjects. Female subjects must be non-pregnant and non-lactating. * 18 to 64 years of age inclusive at Screening * Current or recent history of intolerance to milk and other dairy products * Acceptable Baseline Lactose Intolerance Symptom Scores * Acceptable Result on Baseline Hydrogen Breath Test * Subjects must agree to refrain from all other treatments and products used for lactose intolerance during the study Exclusion Criteria: * Disorders known to be associated with abnormal GI motility * History of surgery that alters the normal function of the gastrointestinal tract * Past or present; organ transplant, chronic pancreatitis, pancreatic insufficiency, symptomatic biliary disease, Celiac disease, inflammatory bowel disease (IBD), ulcerative colitis, Crohn's disease, irritable bowel syndrome (IBS) * Active gastric or duodenal ulcers or history of severe ulcers * Diabetes mellitus (type 1 or type 2) * Congestive Heart Failure * History of Human Immunodeficiency Virus (HIV), Hepatitis B or C * Use of concurrent therapy(ies) for symptoms of lactose intolerance * Uncontrolled BP defined as sitting systolic blood pressure (SBP) ≥160 mmHg or diastolic blood pressure (DBP) ≥95 mmHg at Visit 1 * History of ethanol abuse in the past 12 months * History of drug abuse within 12 months * History or presence of malignancy within the past 5 years (except basal cell or squamous cell carcinoma removed from a sun-exposed area) * Use of any investig…