Broccoli Sprout Extract in Treating Patients With Transitional Cell Bladder Cancer Undergoing Sur… (NCT01108003) | Clinical Trial Compass
TerminatedNot Applicable
Broccoli Sprout Extract in Treating Patients With Transitional Cell Bladder Cancer Undergoing Surgery
Stopped: low accrual
United States7 participantsStarted 2010-04
Plain-language summary
Rationale: Broccoli sprout extract contains ingredients that may prevent or slow the growth of certain cancers.
Purpose: This pilot study is studying the side effects of broccoli sprout extract in treating patients with transitional cell bladder cancer undergoing surgery.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Any patient eligible for superficial bladder cancer
* Patients must be considered fit for surgical resection with curative intent
* No chemotherapy, surgery (excluding transurethral resection of bladder tumor \[TURBT\], BCG or radiotherapy in the prior 4 weeks \[6 weeks for mitomycin C or interferon\])
* No previous treatment/ingestion with broccoli extracts
* Eastern Oncology Group (ECOG) performance status 0-2
* AST and ALT =\< 2.5 times ULN (upper limit of normal)
* Total bilirubin =\< 2.0 mg/dL
* Creatinine Clearance \>= 30 ml/min
* WBC \> 3000 mm\^3
* Absolute neutrophil count \> 1000/mm\^3
* Platelets \> 100,000/mm\^3
* All patients must sign a study-specific consent form indicating that they are aware of the investigational nature of this study
Exclusion Criteria:
* Have participated in any clinical trial involving conventional or investigational drugs or devices within the previous 4 weeks
* Prior radiation to the pelvis
* Intractable urinary tract infection that has not responded to antibiotic treatment
* Active, uncontrolled bacterial, viral, or fungal infection including HIV
* Have had major surgery within 4 weeks of starting therapy (not including placement of vascular access device or TURBT)
* Poor medical risk in the opinion of the treating oncologist due to non-malignant systemic disease
* Pregnant or lactating patients: patients must be postmenopausal or practicing an accepted form of birth control; for patients where pregnancy is a po…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Toxicity as Assessed by National Cancer Institute (NCI) Common Toxicity Criteria Version 3.0