Changes in Brain Function in Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian, Pri⦠(NCT01080521) | Clinical Trial Compass
CompletedNot Applicable
Changes in Brain Function in Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Are Receiving Chemotherapy
United States247 participantsStarted 2010-04
Plain-language summary
This clinical trial is studying changes in brain function in patients with stage I, stage II, stage III, or stage IV ovarian, primary peritoneal, or fallopian tube cancer who are receiving chemotherapy. Learning about the effects of chemotherapy on brain function may help doctors plan cancer treatments.
Who can participate
Age range18 Years
SexFEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Histologically or pathologically confirmed primary diagnosis of stage I-IV ovarian, primary peritoneal, or fallopian tube cancer (any cell type)
* Planning to receive ā„ 6 courses of front-line chemotherapy
* Have not yet received the first course of chemotherapy
* GOG performance status 0-2
* Able to read and understand English
* No uncontrolled or severe cardiovascular disease, including any of the following:
* Myocardial infarction within the past year
* Uncontrolled hypertension
* Congestive heart failure
* No history of head injury with GCS \< 13
* No severe hemiparesis or other condition preventing bimanual keyboard operation
* No distal neuropathy, action tremor, or other motor dysfunction that would substantially decrease keyboard accuracy
* No severe motor or mental slowing (i.e., patient who is disoriented/level C on any criterion as assessed by the person-place-time criteria)
* No other invasive malignancies within the past 5 years except for nonmelanoma skin cancer
* More than 6 months since prior epoetin alfa, darbepoetin, or any investigational forms of erythropoietin
* Patients may receive these agents during chemotherapy treatment as needed
* No prior radiotherapy or chemotherapy
What they're measuring
1
Cognitive function as measured by the HeadMinder Customized Research Tool (CRT)
Timeframe: Up to 6 months after completion of chemotherapy