The Asia-Pacific Flexible Dose Study of Dapoxetine and Patient Satisfaction in Premature Ejaculation Therapy

Inclusion Criteria: * Participants must be heterosexual males and in a stable monogamous, sexual relationship with a female partner for at least 6 months * must score =11 in the Premature Ejaculation Diagnostic Tool (PEDT) * Must have a self-estimated intravaginal ejaculatory latency time (IELT) of = 2 minutes * Must have an International Index of Erectile Dysfunction (IIEF) score a total of \> or = to 21 in 6 questions from the IIEF used to assess for the absence of moderate to severe erectile dysfunction (ED) * Premature ejaculation is not exclusively due to the direct effects of a substance (e.g., withdrawal from opioids) * Must be in good general health with no clinically significant abnormalities as determined by medical history, physical examination, and clinical lab results * Must have a blood pressure =180 mmHg systolic and =100 mmHg diastolic at screening and at the baseline visit * Patient's partner must not be pregnant at screening as pregnancy might affect sexual activity * Participants and partners must agree to attempt sexual intercourse at least 2 times (with a minimum of 24 hours between each event) during the 2-week baseline period and at least 4 times per month during the remainder of the study. Exclusion Criteria: * History of or current major psychiatric disorder such as mood disorder, anxiety disorder, schizophrenia, mania, suicidal ideation, other psychotic disorder * History of alcohol abuse and dependence, non-alcohol psychoactive substance use diso…