Intimal Hyperplasia Evaluated by Optical Coherence Tomography (OCT) in de Novo Coronary Lesions Treated by Drug-eluting Balloon and Bare-metal Stent

Ages Eligible for Study: 18 Years and older Genders Eligible for Study: Both (female sex with child-bearing potential excluded) Accepts Healthy Volunteers: No Inclusion Criteria: * Non-diabetic patients with a stable coronary artery disease, undergoing elective PCI with BMS * de novo non-complex lesions (no bifurcation lesions, no chronic total occlusions, no severe calcifications, no moderate-to-severe tortuosities) located in straight coronary segments. * lesion length ≥10 mm and \<25 mm. * vessel size requiring a single stent with diameter between 3.0 and 3.5mm. Exclusion Criteria: Clinical: * age \<18 years or impossibility to give informed consent, * diabetes mellitus * female sex with child-bearing potential, * life expectancy less than 6 months or any condition impeding clinical follow-up (no fixed address, etc), * significant platelet count alteration (\<100,000 cells/mm3 or \> 700,000 cells/mm3), * gastrointestinal bleeding requiring surgery or blood transfusions within 4 previous weeks, * participation to another study with any investigational device or drug within which is still in the active phase. * history of clotting pathology, known hypersensitivity to aspirin, heparin, cobalt- chromium, paclitaxel, contrast dye, * renal failure with creatinine value \> 2.5 mg/dl, * poor cardiac function as defined by left ventricular global ejection fraction ≤ 30% * acute myocardial infarction within the past 48 hours. * non ST-elevation acute coronary syndrome Angiogra…