"Pilot Study of Armodafinil in Patients With Dementia With Lewy Bodies"

Inclusion Criteria: * Diagnosis of clinically possible or probable DLB using established criteria * Age 50-90 inclusive * Epworth Sleepiness Scale score of 8 or greater * MMSE score between 10 and 26 inclusive * No active medical disorder that could preclude participation in a drug treatment trial over a 12 week protocol * Stable medication regimen over previous four weeks * Absence of psychotropic medications at doses viewed by the clinician to be significantly impacting the patient's alertness during wakefulness * Absence of clinically significant primary sleep-related breathing disorder causing sleepiness as demonstrated by polysomnography (PSG) \[ie, no significant upper airway resistance syndrome (UARS), obstructive sleep apnea (OSA), nor central sleep apnea (CSA) as reflected by a combined respiratory disturbance index (RDI) \<15\] OR adequate documentation of efficacy of treatment for UARS, OSA, and CSA * Caregiver that is with the patient at least 4 hours/day for at least 5 days per week * Patient and caregiver willing and able to participate in all study-related procedures * Patient is capable of giving informed consent, or if appropriate, has caregiver capable of giving consent on the subject's behalf. Exclusion Criteria: * Does not fulfill criteria for clinically possible or probable DLB * Age \<50 or \>90 * Women with intact uterus and not post-menopausal unless pregnancy test performed at screening is negative * Epworth Sleepiness Scale score less than 8 * MMS…